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TRANSCRIPTION (LO's: (Understand the process of gene transcription and…

- - - - Pol 1
        
        Ribosomal RNA's
      - Pol 2
        
        mRNA's for translation into protein
      - Pol 3
        
        Small RNA's (tRNA's)
  - - - Initiation
        
        Regulates gene expression
        
        Requires promotor region
        
        Such as the TATA box
        
        For binding of transcription factors
        
        This attracts RNA polymerase
        
        Major and minor groove
      - Elongation
        
        Pol 2 RNA polymerase begins process
        
        Transcription bubble structure
      - RNA processing + termination
        
        Addition of 5' cap (methylated G)
        
        Protection from degradation
        
        Addition of 3' poly A tail
        
        Splicing:
        
        Introns "junk"
        
        Exons for making protein
        
        Alternative splicing
        
        Alternative combinations of introns
        
        Make different proteins
        
        For Biological efficiency
- - - - Dimer
    - - Dimer
- - - - Translation
        
        Folding