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Pregnancy (3rd trimester (testing (weeks 24-28, fasting at or above 5.3,…
Pregnancy
3rd trimester
increase insulin resistance
risk of hyper
weeks 25-36
testing
weeks 24-28
fasting at or above 5.3
1hr (50 g) at or above 10.6
2 hrs (75 g) at or above 8.9
A1C n/a
goal
fasting: 3.8-5.2
2 hrs: 5.0-6.6
A1C 6.0 of less
in 2-5 % of pregnancy
1st-2nd trimester
increase insulin secretion
decrease. insulin requirement
decrease glucose production
risk of hypo
weeks 1-24
post
testing: 6-12 wks
screen q 3 years w fbs
40-60% likely to develop T2DM w/i 15-20 years
meds
insulin
metformin
perinal mortality & preeclampsia
glyburide (caution)
perinatal mortality & preeclampsia
1st-3rd
worsening of retinopathy
Breastfeeding
lower insulin resistance
morning sickness
DKA