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rbc 5 iron-deficiency anemia (biochemistry (l Fe, h TIBC (transferrin)…
rbc 5 iron-deficiency anemia
CBC
l MCV, l MCH, l Hb
h RDW
l reticulocyte
clinical
anemia
pallor
iron-deficiency
angular stomatitis, glossitis
koilonychia
biochemistry
l Fe
h TIBC (transferrin)
negative acute phase protein
l Fe saturation (Fe/TIBC)
l ferritin
:smiley:
bone marrow aspiration
macrophage x hemosiderin
normoblast x siderotic granules
blood film (dimorphic!)
microcytic, hypochromic
pencil cell
treatment
treat bleeding
(oral) ferrous sulphate (duodenum, jejunum)
extravascular hemolysis
RE system (marrow, liver, spleen)
cells: ferritin (hereditary hemochromatosis)
macrophage: hemosiderin
blood
Hb (65%)
(bleeding)
blood
(negative acute phase protein) transferrin
(absorption, excretion)
bone marrow
normoblast