Please enable JavaScript.
Coggle requires JavaScript to display documents.
rbc 2 megaloblastic anemia (CBC (h MCV, n MCH, l Hb, l reticulocyte, l WBC…
rbc 2 megaloblastic anemia
CBC
h MCV, n MCH, l Hb
l reticulocyte
l WBC, l platelet
clinical
anemia
pallor
bilirubin
(lemon yellow) jaundice
megaloblastic
angular stomatitis, glossitis
neural tube defect, (b12) subacute degeneration of cord: peripheral neuropathy
sterile
biochemistry
red cell folate, active vitamin B12
high: uncon bilirubin; high LDH
bone marrow aspiration
hypercellular
fine chromatin
myelocyte, band
blood film (dimophic!)
oval macrocyte
(nuclear) Howell-Jolly bodies, (ribosome) basophilic stippling
hypersegmented neutrophil 6
treatment
drugs
(intramuscular) hydroxocobalamin
(oral) folic acid
(caution)
increase erythopoiesis: hypokalemia
v b9 x b12: increase subacute degeneration of cord, increase peripheral neuropathy