Please enable JavaScript.
Coggle requires JavaScript to display documents.
Meglitinide: non-sulfonyurea secreatagogue (benefits (Repaglinide (decr.…
Meglitinide:
non-sulfonyurea secreatagogue
side effects
weight gain
mod. risk of hypoglycemia
drugs
Repaglinide
GlucoNorm
start: 0.5 mg
max: 4 mg
nateglinide
Slarlix
start:
max: 720 mg
Pathophysiology
act on B cells; losely attached; requires high bs
stimulate insulin secretion
contraindication
with insulin
timing
onset
peak
1 hr
duration
4-5 hrs
full effectiveness
benefits
decr. pc bs
Repaglinide
decr. A1C by 0.7%
for irregular meals
for shift work
Nateglinide
decr. A1C by 0.5%
can use at any eGFR
hold if meal missed