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Immune system (Second line (innate) (Inflammation (Inflammatory mediators,…

- - - - Interleukin-1
  - - - Wandering macrophages
      - Fixed macrophages
        
        • Histiocytes
        • Kupffer cells
        • Alveolar macrophages
        • Microglia
        • Tissue macrophages
        • Langerhans cells
  - - - • Histamine
        • Leukotrienes
        • Kinins
        • Prostaglandins
        • Complement system
- - - - Clonal selection
        (via Interleukin-2)
        
        Memory B-cells
        
        Plasma cells
  - - - T-Helper cell
        
        Interleukin-2
        
        Clonal selection
        
        • Cytotoxic T-cells
        • Memory T-cells
        • Helper T-cells
      - Cytotoxic
      - Self-tolerance & self-recognition
      - Regulatory T-cells
- - - - T-Lymphocytes
        
        • Cytotoxic
        • T-Helper cells
      - B-Lymphocytes
        
        • Plasma cell
        • Memory B-cells