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Calabar beans & Physostigmine (Physostigmine (Luka) (Characteristics…
Calabar beans & Physostigmine
Physostigmine (Luka)
Uses
Used to treat gluacoma, not everybody is allowed to produce this as it is poisonous to humans if not used correctly
Characteristics
Chemical
Physostigmine has a very low flammability, it is extremely toxic and not reactive with many other substances
Physical
The beans used to make Physostigmine are poisonous to humans and can result in death if consumed. It melts at 102 C, It is soluble in water
Process
The process of making Physostigmine from calabar beans is known as synthesis, The physostigmine extract comes directly from these beans and they ended up going from a poison everyone tried to avoid, to a renowned medicine
History
A man called Percy Lavon Julian was the first to synthesize this drug and use it to treat gluacoma in 1936, he was awarded a Nobel Prize for his discovery as it helped treat people around the world
The physostigmine in calabar beans before the medical discovery used to be used in many african tribes as a crude way of execution
How does it work
Physostigmine can be used to treat glaucoma as it passes the blood-brain barrier.
It also stimulates Nicotinic and muscarinic receptors.
Calabar Beans (Doyeon)
Physical Characteristics
Leguminous Plant
Looks like a normal bean
Melts at 102 C
Chemical Characteristics
Poisonous to Humans
Uses
Used to make physostigmine, which is inside the bean. The substance can be poisonous if used incorrectly.
It shouldn't be consumed raw as it can kill you with it's poison.
History
Calabar beans were used in native African tribes as an way to execute people with the poison. Many people didn't chew the beans to live, because the poison is contained inside the beans.
Growing the Beans
The beans can be grown normally, and were mostly grown in Africa
