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imm 5 hypersensitivity (type 1: allergy (immune mediator (IgE), mechanism…
imm 5 hypersensitivity
type 1: allergy
immune mediator
IgE
mechanism
IgE binds mast cells & basophils
manifestations
anaphylaxis
food allergy
hay fever
asthma
type 2: antibody-mediated
immune mediator
IgM, IgG
mechanism
antigen-antibody
manifestations
adverse transfusion reactions
autoimmune hemolytic anemia
type 4: delayed type hypersensitivity DTH
immune mediator
T cell
mechanism
macrophage
manifestations
TB
type 3: immune complex-mediated
immune mediator
immune complex
mechanism
neutrophils
manifestations
RA
SLE
glomerulonephritis