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Basal cell carcinoma (clinical (patch/nodule, rolled edges with central…
Basal cell carcinoma
clinical
patch/nodule
rolled edges with central crater
pearly edges
telangectasia
pink or pigmented
aetiology
UV exposure
genetic predisposition
incidence
v.common in NZ
M>F
pathophysiology
mutations in PTCH tumor suppressor gene (part of the hedgehog signalling pathway)
can be triggered by UV exposure
treatment
medical
cryotherapy
photodynamic therapy
imiquimod cream
fluorouracil cream
radiotherapy
surgical
excision biopsy
3-5mm clearance
mohs micrographically controlled excision
superficial skin surgery
curettage
shave
electrocautery
complications
disease
melanoma
metastasis
treatment
surgery
scar
recurrence
bleeding
infection
medicine
recurrence
definition
locally invasive non-melanoma skin cancer
diagnosis
clinical
ancillary
biopsy
prognosis
good - curative