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Crohn's (pathophysiology (mouth to anus (commonly affects terminal…
Crohn's
pathophysiology
transmural inflammation
skip lesions
cobblestone appearance
strictures
mouth to anus
commonly affects terminal ileum and colon
treatment
medical
induce remission
glucocorticoids (1st)
enteral feeding
5-ASAs (2nd)
mesalazine
azathioprine or mercaptopurine
used as add on
methotrexate as alternative
metronidazole
peri-anal disease
infliximab
refractory and fistulating disease
maintain remission
azathioprine or mercaptopurine (1st)
methotrexate (2nd)
5-ASAs
if patient has had previous surgery
mesalazine
surgical
segmental small bowel resection
stricturoplasty
lifestyle
smoking cessation
avoid NSAIDs?
avoid COC?
definition
form of IBD
aetiology
RF
incidence
clinical
diagnosis
ancillary