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BACTERIOSTATIC Inhibitors of Protein Synthesis (Macrolides: (-thromycin)…
BACTERIOSTATIC Inhibitors of Protein Synthesis
Tetracyclines: (-cyclin)
Adverse effects
GI Irritation (nausea, vomiting diarrhea)
Bind to Ca in teeth and cause staining
Hepatotoxic
Nephrotoxic
Supra infection of Candida or C. Diff
Interactions
Ca products
Fe supplements
Mg laxatives
Most antacids
Given as a first line drug for:
Rocky Mountain spotted fever
Chlamydia trachomatis
Lyme disease
Bacillus anthracis
H. Pylori
Macrolides: (-thromycin)
Similar to penicillin-common replacement
Give as a first line drug for:
Legionella pneumonia
Bordetella pertussis (whooping cough)
Corynebacterium diphtheriae
CYP450 INHIBITOR
Erythromycin
Azithromycin (ZPACK)
Clarithomycin (BAD DRUG)
Clindamycin
POTENTIALLY FATAL (C. Diff) DIARRHEA
TX of Group A streptococcal infection
TX of gas-gangrie associated Clostridium perfringens
Linezolid (Zyvox)
MUST BE RESERVED FOR MRSA, VRE
We don't want PTs becoming resistant to this drug
Adverse effects
GI Irritation
Myleosuppression(suppression of one marrow) CHECK WBC