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Embryology (Neuralation
Formation of neural tube (Transformation of…
Embryology
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Catchup
Week 1
- 1,Fertilisation (zona pellucida)
- Late blastocyst (trophoblast)
- 4, Implanatation: Inner cell mass
Week 3
- First missed menstrual period + Primitve streak
- Stage 7: Migration of mesenchymal cells
- Trilaminar embryo + Amnion + primitive streak + migration of cells from primitive streak
- Stage 8: Neiral plate + primitive streak
- Neural plate + neural groove + Somite + primitive node + primitive streak
- Stage 9: Brain, Neural groove + Somite + Thyroid gland development
- Neural groove, first pairs of somites + primitive streak + connecting stalk
Week 2
- Amniotic cavity + Bilaminar embryonic disc
- Lacunae appear in syncytiotrophoblast + Primary umbilical vesicle
- Cytotrophoblast + Amnion + primary umbilical vesicle + closing plug
- Extraembryonic mesoderm + coelom
- Connecting stalk + Amnion + embryonic disc + prechordal plate
Ectoderm
Neuroectoderm
Neural tube
- CNS
- Retina
- Pineal body
- Posterior part of pituitary gland
Neural crest
- Cranial and sensory ganglia and nerves
- Medulla of suprarenal gland
- Pigment cells
- Pharyngeal arch cartilages
- Head mesenchyme and connective tissue
- Bulbar and conal ridges in heart
Derivatives
- CNS
- Peripheral nervous system
- Sensory epithelium of ear, nose and eye
- Epidermis including both hair and nails
- Subcutaneous glands, mammary glands, pituitary gland, enamel of teeth
Neu
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Dev of neural tube
- Masses of cells detach themselves from lateral side of neural plate and form Neural Crest
- End of third week: neural folds begun move together and fuse: neural plate to Neural Tube
- Neural tube separates from surface ectoderm, surface ectoderm fuse + differentiate - epidermis of skin
- Neuralation completed 4th week
Closure of Neural tube
- Until fusion is complete, cephalic and caudal ends of neural tube communicate wtih amniotic cavity by: cranial and caudal neuropores