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Joints (Rheumatoid arthritis (S/Sx (small joints affected then larger,…
Joints
Rheumatoid arthritis
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prod, nonsuppurative proliferative & inflammatory synovitis
dest, articular cartilage & ankylosis
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S/Sx
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swollen, warm, stiff, painful, on arising activity
malaise, fatigue, gen. MSK pain
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central zone, num lymphoctes & plasma cells
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Dx
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sterile, turbid, synovial F w/ dec viscosity
Tx
Cortico steroid, methrotrexate, antagonist of TNF
relieve apin, inflammation
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Reactive Arthritis
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nongonococcal urethritis, cervicitis, conjunctivitis
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Psoriatic A
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10% psoriatic population devt
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Osteoarthritis
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Primary DJD
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knees, hand affect in women,
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Secondary DJD
previous dmg, congenital abnorm joint w/ systemic disorders
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