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Antibiotic Resistance (Efflux Pumps (ABC (ATP-binding casette) (S.…

- - - - Enterococci/MRSA
- - - - Break B-lactam ring after entry
    - - 1st/2nd gen Cephalos
    - - 3rd gen Cephalos and Aztreonam
    - - Not inhibited by Clav (ESCAMPP)
    - - Hydrolyse ALL B-lactams
- - - - Can't cross inner or outer membrane to reach ribosome
  - - - B-lactams can't reach PBP