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Sertoli: Proteins (Androgen Binding Protein (ABP) (Expression (Regulation…
Sertoli: Proteins
Androgen Binding Protein (ABP)
Job
Mediator for spermatogenesis
Expression
Encoding
Chromosome 17
ABP-SHBG gene
Regulation
β-HLH
Factors
SPZ1
CREB/CREM
cAMP and FSH
Upregulation ABP
Promoter(s)
PA secondary promoter
P1 Primary promoter
What is/are androgen(s)
Are hormones
structure based off of cholesterol
are strongly expressed in males
are subtly expressed in females
Source
Testosterone is a potent example
Are important for male development
development of the reproduction system
in the case of sertoli cells, sperm production
Source
Inhibin
Job
Mediator for spermatogenesis
Expression