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Influenza Pandemics (H5N1 Avian Influenza (Control (Vaccination (Poses…

- - - - Seen as both high and low
  - - - Rationale behind unusual age prevelance
      - Very elderly had seen a H1N1 with similar antigen before
        
        Therefore had partial acquired immunity
      - People aged ~40yrs at 1918 had seen a H1N3 previously
        
        Also had very partially immunity
      - People aged 20-30yrs had not seen anything like H1N1 before
  - - - Showed reassortment prior to 1918 between avian and swine
      - Then to humans
      - Then back to pigs after 1918
  - - - Known as r1918
    - - Ferrets are a very good human model for influenza
- - - - Same as 1918
      - This was not mirrored in other countries
      - Probably only seemed high at start as only severe cases were reported
        
        Wasn't that virus mutated to be less pathogenic
    - - Not elderly as they already had seen similar H1N1 as in 1918
- - - - Poses porblems for elimination