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Lachlan (4 1/2 y.o. (Quiet, Difficulty joining group activities, frequent…

- - - - NO DYSTROPHIN
        
        Unstable membrane - breaks with contraction - especially eccentric
        
        Necrosis & degenerating muscle fibres
        
        Attempt at regeneration
        
        Regeneration is eventually exhausted
        
        muscle fibres replaced with connective & adipose tissue
        
        1 more item...
        
        increases membrane permeability
        
        Calcium enters
        
        Causes protein breakdown & cell death
        
        CK exits - into bloodstream
        
        2 more items...
  - - - leads to functional ischaemia
        
        impaired vascular relaxation
- - - - Genetic disorder/trauma at birth
      - Varying symptoms
      - Affects speech
      - can affect eating too
      - can understand but cannot express
  - - - Very common
    - - likes looking at lights
  - - - Infections/ genetic mutation cause
      - Late/poor achievement of milestones
      - Behavioural problems
      - cognitive impairment
      - IQ test - 4 to 6 y.o.
    - - MRI & movement tests
- - - - Stretching & splinting