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COPD (Emphysema (Definition (Irreverisble, Enlargement, Distal to terminal…

- - - - Lung inflammation
        
        Protease release
        
        Lung damage
        
        Loss of elastin
        
        Loss of elastic recoil
        
        Airway collapse on expiration
        
        Narrowed bronchial lumen
        
        Goblet cell hyperplasia
        
        Inflammatory infiltrates
        
        Thickening of bronchial wall with smooth muscle hypertrophy
      - Oxidative stress #
  - - - Weight loss
      - Dyspnoea
      - Cough
      - Wheeze
    - - Barrel chested
      - Prolonged expiration vs inspiration
      - Hunched over tripod position
      - Pursed lip breathing