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Liver Disease (autoimmune hepatitis (types (I (ANA, anti-smooth muscle),…
Liver Disease
autoimmune hepatitis
progressive inflammatory liver condition
75% F
40% have FHx of autoimmune disease
predominantly T cell mediated
aminotransferases high
serum gammaglobulins high
types
I
ANA
anti-smooth muscle
II
anti-LKM1
steroid and azathiprines induce remission in >80%
associated with malignancy risk
viral hepatitis
Hep A
Hep B
Hep C
Hep D
Hep E
genetic
haemochromatosis
wilsons
alpha1-antirypsin
acute hepatic failure
NAFLD
cirrhosis
alcoholic liver disease