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reactions (SN1 (v=k[electrofil], << secondary < tertiary, favored…
reactions
SN1
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polar protic solvent, as it can stabilize the formation of a carbocation
weak nucleophile, weak base
stabile carbocation, which result in racemic
solvent is often the nucleophile, polar protic
tertiar, allylic, bensylic substrate react easily with SN1
SN2
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polar aprotic solvent (DMF, DMSO)
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leaving group, realativly weak base (iodide ion)
nucleophile/base: negativly charged, unsteric hindered ions.
reagent
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methoxide ion, strong nucleophile and strong base
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--OH (-) strong base, strong nucleophile
E1
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strong nucleophile, weak base
secondary alcohole undergoes an E1 reaction if you use something like sulfuric acid or phosphoric acid and heat it up. The leaving group will be water.
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E2
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the beta-carbon connected to highest numbers of other carbons will give away a H(+) (Zeitsev's rule) as long as it's not steric hindered
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