Please enable JavaScript.
Coggle requires JavaScript to display documents.
talk Szeged (main assumptions (folding (force fields), docking (induced…
talk Szeged
main assumptions
-
docking
induced docking, flexibility...
-
-
news on folding
Ramachandran
Rather than using a modified ff knowledge based, we employ a Ramachandran surface to pilot folding
Ribosome
Mimicking the effect of ribosomes, we assist the folding elongating the peptide by one residue
Chaperons
It is well known that Hsp70 and other chaperons assist folding stabilizing newborn peptides. We mimick the effect of chaperons, adding restrains to the folded peptide portion
-
-
goals of drug discovery
limits
For every complex problem there is an answer that is clear, simple, and wrong. H. L. Mencken
MD, CG, FF research, fishing for partners.
-