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OSMOREGULATION (Counter current mechanism and renal clearance (Loop of…
OSMOREGULATION
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Differentiate between ;
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What happen if FAILED to osmoregulate ? EDEMA (Dropsy) ; Condition where failure to osmoregulate which causes freshwater fish to swell due to excessive fluid build-up
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Transport maximum (Tm)
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amt of particular substance excreted directly proportional to the amt filtered by glomerular capsule
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Osmoregulation Mechanism
Hypothalamus (influences water excretion and thirst) synthesized Antidiuretic hormone ADH in pituitary gland
Hyperosmotic ECF ( extracellular fluid stimulates the secretion of ADH. ADH increases water reabsorption in the distal tubules and collecting ducts in of the kidney
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Concentration of Urine
NaCl and urea contribute to the osmolarity of the extracellular fluid (ECF)> reabsorption of water in the kidney and concentrates the urine > water diffuse out from tubule to interstitial fluid / ECF > tubular fluid concentration increases
Osmolarity increases with distance from the cortex and reach the max in innermost spaces of the medula
Loops of Henle and collecting ducts cooperate and responsible for the osmotic gradient that concentrates the urine
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