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Gram (-) bacteria of GI (Vibrio Cholera (gm (-), curved rod, halophilic,…
Gram (-) bacteria of GI
Vibrio Cholera
gm (-), curved rod, halophilic, facultative anaerobes
highly motile bc flagellum, toxin co-regulated pili, cholera toxin: change water/ion flux
causes loss of fluids and electrolytes, hypovolemic shock, acidosis
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A-B toxin: ADP ribosylates Gs, ↑AC, ↑cAMP, ↑Cl loss, ↑Na loss, ↑water loss
diagnosed: gm (-) curved, PCR
treated: rehydration (water & electrolytes), antibiotic sometimes
Prevented: avoid raw shellfish, short-term vaccine, water purification, proper sewage treatment
transmitted by contaminated food, water
No Inflammation :red_flag:, colonize epithelial surface
Watery Diarrhea (ETEC)
watery diarrhea, cramps , vomiting
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Helicobacter pylori
gm (-), curved rod, motile bc flagella,
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virulence factors: flagella, chemotaxis, urease :red_flag:, adhesins
diagnosed: gastric biopsy, isolate bacteria, test urease (+)
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