Please enable JavaScript.
Coggle requires JavaScript to display documents.
Stress and Fatigue 2 (FOOD (CAFFEINE (Caffeine amplifying cortisol…
Stress and Fatigue 2
FOOD
-
During times of stress, cortisol mobilises glucose into the bloodstream by
gluconeogenesis, decreased insulin sensitivity, amino acid mobilisation, and
protein catabolism
-
Skipping meals or eating meals or snacks rich in simple carbohydrates can
create a hypoglycaemic state, which induces the stress mechanism and release
of cortisol
CAFFEINE
Caffeine amplifying cortisol production many hours after ingestion
– this amplification effect persists with regular use of caffeine
Caffeine should be avoided by individuals who are under chronic stress, as
well as by those who wish to avoid adrenal dysfunction
POTASSIUM
One of the key dietary recommendations to support the adrenal glands is to
ensure adequate potassium levels within the body
SODIUM
-
Most have a dietary potassium-to-sodium (K:Na) ratio of less than 1:2. In
contrast, most researchers recommend a dietary K:Na ratio higher than > 5:1 for
health
– A natural diet rich in fruits and vegetables can produce a K:Na ratio higher than 50:1, as most
fruits and vegetables have a K:Na ratio of more than 100:1
-
MAGNESIUM
-
-
-
-
When magnesium (Mg) deficiency exists, stress
paradoxically increases risk of cardiovascular damage including hypertension, cerebrovascular and
coronary constriction and occlusion, arrhythmias and sudden cardiac death (SCD)
ASCORBATE
-
Pregnenolone is one of
the initial steps in cortisol, DHEA-S, and sex hormone production
During chemical, emotional, psychological, or physiologic stress, the urinary
excretion of vitamin C is increased
-
-
-
VITAMIN E
Acute or chronic exposure to stress increases free radical formation
throughout the body but specifically in the adrenal cortex
In response to stress, Vitamin E has been shown to protect the
adrenal cortex from free radical damage and reduce cortisol
production
-
-
-
-
FOOD ALLERGY
As far back as 1930, pioneering allergist Albert Rowe began noticing that anxiety
and fatigue were key features of food allergies
With the popularity of chronic fatigue syndrome, many physicians and other
people are forgetting that food allergies can lead to anxiety as well as chronic
fatigue
-
AMINO ACIDS
-
TAURINE
Improves mood for patients who are very anxious
– Directly reduce excess SNS activity by acting as an antagonist to vasopressin
and noradrenaline
PHOSPHATIDYLSERINE (PS)
Often used for improved cognitive function, PS has been shown to have potent
inhibitory effects on the HPA axis
Monteleone, et al., found oral dosages of 400 mg/day displayed no statistical
difference from placebo, while administration of 800 mg/day had significant
inhibitory effects on the HPA axis
STRESS & INFLAMMATIION
ACTIVATED IMMUNE SYSTEM
PRODUCES CELL PRODUCTS
CYTOKINES
TNF alpha
STIMULATE CRF SECRETION
ACTIVATES
HPA
axis
ULTIMATELY
simultaneous changes in the serotonergic
and noradrenergic systems, combined with the activation of peripheral
and central macrophages that increase the proinflammatory cytokine
concentrations in the brain and blood, also play a critical role in predisposing
to anxiety and depression.
-
-
-
The rise in proinflammatory cytokines (IL- 6, TNF-alpha and IFN-alpha) that
frequently occur in major depression further increase the secretion of
glucocorticoids.
-
-
-
-
-
CORTISOL
FUNCTIONS
Stimulation of gluconeogenesis, particularly in the liver
This pathway results in the synthesis of glucose from non-hexose substrates such as
amino acids and lipids
Enhancing the expression of enzymes involved in gluconeogenesis is
probably the best known metabolic function of glucocorticoids
-
-
-
B6 - PYRIDOXINE
Pyridoxine deficiency has been identified as a significant predictor of
increased overall psychological stress
-