GABA (γ-aminobutyric acid), is a Cl- ion channel
• Activated by GABA, inhibitory neurotransmitter in the CNS.- five subunits (α, β, and γ)- “GABA-A” isoform consists of two α1, two β2, and one γ2 subunits - 2 GABA binds at two locations between adjacent α1 and β2 subunits.