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SURFACE MODIFICATION (Protein surface interactions (Protein properties…
SURFACE MODIFICATION
What is a surface
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What is an interface
Liquid/Liquid: Both phases highly mobile: Shape of interface defined by surface tension. Molecules may migrate between them: controlled by partition coefficient
Solid/Liquid: Liquid may dissolve surf atoms: surf changes.
liquid molec at interface can be higher ordered than in the bulk.
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Biological methods
Goal: To control cell and tissue responses
to an implant by immobilizing
biomolecules on biomaterials :checkered_flag:
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Patterning
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:checkered_flag:Goal: Alter surface properties
of biomaterials in a
controlled manner resulting
in a geometric design of
well defined regions
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