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Energy, Enzymes, Metabolism (how enzymes works (temporarily add chemical…
Energy, Enzymes, Metabolism
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Kinetic
examples
Heat (breaks the chemical bonds, releasing energy)
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energy barriers
transition state: the reactive condition of the substrate aftere there has been sufficient activation energy to initiate the reaction
enzymes lower barrier, but do NOT affect equilibrium
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inhibitors
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uncompetitive
binds at a different site other than the active site so the substrate changes shape and cannot respond to ligand
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inhibition
the final product inhibits the enzyme that catalyzes the commitment step (other reactions happen in sequence after the catalyzed reaction occurs) so that less product will be made if no more is needed