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Pharmacodynamics: How drugs produce their effects (Endogenous substances,…
Pharmacodynamics:
How drugs produce their effects
Endogenous substances
Mimics/ replaced
Injection of insulin
For Diabetes Type 2
Vitamins/minerals insufficiency
Take supplements
Beta-1 agonists
Eg:
Isoprenaline mimics noradrenaline
Antagonized
Eg:
Propranolol
(Beta-adrenergic antagonists)
Binds to
Beta-adrenergic receptors
Antagonizes
Adrenaline/ noradrenaline
Change the environment
Antacids
Neutralises
Gastric hyperacidity
Endogenous substances production
Increase
Eg:
Sulfonylurea drugs
Induces
Pancreatic cells
To produce
More insulin
Decrease
Eg:
Simvastatin
Inhibits
Synthesis of cholesterol