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molecular: beta oxidation-carnitine shuttle (fatty acids (very long chain,…
molecular: beta oxidation-carnitine shuttle
(outer mito mem) CPT-1
acyl-CoA
carnitine
CoA
acyl-carnitine
(outer mito mem) thiokinase
acyl-adenylate
acyl-CoA
diffuse across outer mitochondrial membrane
(inner mito mem) CPT-2
CoA
acyl-carnitine
carnitine
acyl-CoA
carnitine-acyl carnitine translocase
fatty acids
very long chain
long chain
long chain (major)
carnitine shuttle
medium chain
diffusion into mitochodria
short chain
diffusion into mitochodria