Etiology: May be alcohol abuse, chemotherapy, inflammation, hypertension, CAD, muscular dystrophy, pregnancy, valvular disease, or poor nutrition
Pathophysiology: extensive damage to the myofibrils and interference with myocardial metabolism; fibrosis of myocardium and endocardium, dilated ventricles (LV is worst), systolic fx is impaired; mural wall thrombi prevalent
Heart becomes weak. The chambers get large. The heart cannot pump enough blood to the body
Clinical Manifestations
- May be asymptomatic for years
- Fatigue and weakness
- Heart failure (left)
- Palpitations
- Dysrhythmias or pulmonary emboli
- S3 and S4 gallops
- Pulmonary crackles
- Anorexia, N&V
- hepatomegaly
- JVD
- Moderate to severe cardiomegaly
Treatment:
- Symptomatic treatment for heart failure
- Vasodilators (calcium channel blockers)
- Nitrates
- Beta blockers
- ACE inhibitors
- diuretics
- Anticoagulation therapy
- Control of dysrhythmias
- Ventricular Assistive Device (VAD)
- Surgery: heart transplant
Diagnostic Testing
- Echocardiography
- EKG
- Cardiac catheterization
- Chest Xray
- Lab studies (BNP- heart failure)
Goals
- Alleviate symptoms of HF
- Improve CO and quality of life