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Skeletal Muscle (Muscle contraction (Shortening: activated and shortened:…
Skeletal Muscle
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Muscular regeneration
Satellite cells
undifferentiated, mitotically quiescent mononuclear myogenic preursor cells
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- Muscle fibre: muscle cell:
Long parallel bundles of nucleated cells
Myofibrils - contract
- Sarcoplasm: cytoplasm of muscle fibre
- Sarcolemma: muscle fibre plasma membrane
- Sr: smooth Er of muscle cell
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Muscle contraction
- Nerve impulse
Ach bind sarcolemma
- Wave of depolarisation
- Ca2+ released from Sr
- Ca2+ binds to troponin, conformational change: tropomyosin moves out the way- cross bridge
- ATP
- Contraction
Actin: thin filament: I band
Myosin: thick filament: A band
- Centre I band: Z line
- Centre of A band: M line