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A6 typhoid fever (transmission (urine, feces, blood, bone marrow, invade…
A6 typhoid fever
transmission
urine, feces
blood, bone marrow
invade intestinal microfold folds: hemorrhage, perforation
travellers: fecal-oral
salmonella typhi
Vi antigen
H antigen
O antigen
human is the only host
diagnosis
gram stain
culture
serology
widal's test
clinical
fever
(pulse x increases with temperature) pulse-temperature deficit
malaise
rose spot
myalgia
leukopenia
vaccine
oral
paraenteral
carrier: typhoid mary
shedding in feces
stick to gallstone
treatment
fluoroquinolone