Please enable JavaScript.
Coggle requires JavaScript to display documents.
A9 uric acid (nucleotide (base (pyrimidine (T, C), purine (A, G)),…
A9 uric acid
-
nucleotide
breakdown
chemotherapy, trauma, starvation
turnover
malignant: e.g. myeloproliferative, lymphoma, leukemia
-
purine production
-
de novo synthesis
-
(glycogen stroage disease type 1) glu-6-phosphatase deficiency, inc rib-5-P
dec EXCRETION
-
75% kidney
-
catecholamines, cyclosporin
-
alcoholism
-
purine production
oxidation of ethanol, ATP, AMP
-
-
gouty arthritis
-
-
-
-
inflammation: red, swell, warm, pain
-
-