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First Year Jaundice (Before Two Weeks (First Day (Hemolytic (IntraVascular…

- - - - IntraVascular
        
        Postive Coombs Test
        
        InCompatbility Rh or ABO
        
        ABO incompatibility
        
        2) Usually in the First Child and Less sever Later ( Preexisting AntiBodies )
        
        3) Most Common Mother : O and the Baby : A
        
        4) ABO protects from RH
        
        1) Mother Must Be O and the Child Can be A, B , AB
        
        TYPE ( A , B ) blood have Have Ig-M antibodes Which Doesn't Cross Placenta
        While Type ( O ) has IG-G Which Cross the Placenta
        
        Rh Incompatbility
        
        1) Less Common But More Sever ( Mother Negtaive , Baby Postive )
        
        2) Usually after the 2nd child ( Sentized AntiBodies )
        
        4) ABO protects from RH
        
        Negative Coombs Test
        
        SpheroCytosis and ElpitoCytosis
        
        G6PD
        
        Alpha_thalassemia
        
        Defect in Alpha Gene Present Since Birth Due Contribuation in Hemoglobin F Which is High Until 6 Months
      - Coneclead Hemorhage
        
        PolyCehtmia
        
        CephaloHematoma
    - - Type 1 - Resscive - Complete Absence of UGT1A enzyme
        
        Presenst As High Unconjucated HyperBIlirubmenmia Above 25 , With No Evidance of Hemolysis ( Coombs Negative , Not Riticulocytsis , Or Anemia )
        
        High Risk of Kernictures
- - - - G6PD
      - ShperoCytosis
      - HexoKinase Defiency
      - Pyurvate Kinase Diefency
      - Appears in the First 24 Hours
    - - PolyCethemia
      - CephaloHematoma
      - Appears From 24 Hour to 72 Hour
- - - - Billary Atresia
        
        3 - 4 Weeks Onset Jaundice Must Be Before Two Months
        
        Presistant ACholic Stool
        
        Usually Normal Weight Gain
    - - HepatoCeullar
        
        INFECTION
        
        UTI and Sepesis
        
        TOXINS (
        
        Total Parentral Nutrition
        
        IDIO
        
        Attacks of Acholic Stool Seprated by Normal Stool
      - Obsturctive
        
        Caroli
        
        Algalili Syndorme
    - - Attacks of Fits and Vomiting ( Due to HypoGlycemia and infection)
      - Galaectosemia
        
        Maybe Other Anomilies Such as : Catarct
        
        HepatoSpleenMegaly
      - Sepsis
      - Attacks of Presistanct ACholic Stool
    - - At Birth Jaundice Onset
      - Ante Natal Fever and Rash
    - - Billary Atresia
        
        Presistanct ACholic Stool and Jaundice Usually Appears in the End of First Month ( 3rd or 4th Week ) , Hepatomegaly , Healthy Baby ,
        
        Must Be Corrected before Two Months Or Bad Prognosis
        
        Kasai Procedure
        
        UltraSound Shows :- Triangular Cord Sign
        
        Liver Biopsy Detects Only INTRA-Hepatic Involvment So May be not Conculsive ( may Need Laprotomy )