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Gottesman (2010) - The Medical Model (Results (Group A (two parents…
Gottesman (2010) - The Medical Model
Aim
Looks at the incidence of schizophrenia & bipolar and whether it is heredity
Participants
Population of Denmark alive in/born after 1968 with a clear link to their bio parents in the Civil Registration System
2m6 people were studied.
Those received diagnosis of schizophrenia/bipolar affective/unipolar depression were identified from the Psychiatric Central Regiser
Couples where both had been admitted to a psychiatric hospital were identified for study
Control group with one parent admitted, neither parent admitted, and general public (nothing regarding mental illness) were also studied.
Results
Group A (two parents admitted with a diagnosis of schizophrenia - 270)
26 (27.3%) admitted with schizophrenia diagnosis
40 (39.2%) admitted with schizophrenia/schizophrenia related disorders
Group B (one parent admitted with schizophrenia ~ 13k)
473 (7%) admitted with schizophrenia diagnosis
Group C (neither parent admitted with schizophrenia ~ 2m2)
9384 (0.86%) admitted with schizophrenia diagnosis
Group D (general population ~ 2m7)
14 938 (1.12%) admitted with schizophrenia diagnosis
Group E (both parents admitted w/ diagnosis of bipolar disorder)
4.8% admitted with schizophrenia diagnosis
Group F (one parent admitted with diagnosis o schizophrenia and one with bipolar)
15.6% admitted with a diagnosis of schizophrenia
Conclusions
Offsprings of dual matings diagnosed with schizophrenia constitute a super high risk sample of schizophrenia. Higher if two parents rather than just one.
Supported that genetics do
play a part
in inducing mental disorders like schizophrenia and bipolar (4.4% if one parent, 0.48% if no parent for bipolar)