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Neurohistology (Glia (Astrocytes (support, Reactive gliosis, BBB, GFAP,…

- - - - Merkel disks
        
        Hair folicles
        
        position
        
        Static touch
      - Pacini corpuscles
        
        Dermis
        
        ligaments
        
        Joints
        
        vibration
        
        deep pressure
      - Meissner corpuscles
        
        epidermis of hairless skin
        
        position
        
        dynamic touch
      - Krause
        
        cold
        
        skin
        
        mucosa
        
        conjuntiva
      - Ruffini corpuscles
        
        dermis
        
        skin stretch
        
        pressure
    - - Muscle spindles
      - Golgi tendon organ
- - - - Mesocortical
        
        negative symptoms
      - Mesolimbic
        
        positive symptoms
      - Nigrostriatal
        
        Parkinson/extrapyramidal effects
      - Tuberoinfundibular
        
        Release prolactine
      - increased in schyzophrenia
      - decreased in Parkinson and depression
    - - decreased in anxiety and depression
      - Raphe nucleus
    - - locus ceruleus
      - reticular formation
      - solitary tract
      - adrenal medulla
      - reduced in deprssion
      - increased in anxiety and mania
  - - - paracrine signal-->memory formation
      - reperfusion injury
    - - pain; excitatory
    - - Inhibitory
      - ttx of supraventricular tachycardia
  - - - inhbitory in Spinal Cord
      - Stychnine is glycine antagonist
    - - Meynert
      - Learning, short term memory
      - arousal, reward
      - reduced in Alzhimer and Hudington
      - increased in Parkinson
    - - excitatory
      - NMDA receptors (N metyl D aspartate)
      - origins GABA
      - hippocampus: learning and memory
      - stroke and seizure-->Ca influx--> neuron damage
    - - endorphin
      - enkephalins
      - dynorphins
    - - reduced in axiety
      - reduced in hundington
      - nucleus accumbens
      - benzo and barbiturates increase GABA function
      - Inhibitory