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Immune System (Innate (phagocytosis, complement: inflammation, barriers to…
Immune System
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Normal Function
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involves sufficient: specificity, intensity, and duration
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tolerate self, recognize/destroy damaged self; recognize/destroy wide variety of pathogens
Immunization
passive: exposed to pathogen and given antiserum of antibodies, usually IgG BUT there is no memory produced.
adoptive transfer: taking cells from one animal and transferring them to another; is a long term transfer of memory cells; not seen in humans but in literature
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Normal Response
recognize infection: TLRs, NK cells, Type I IFNs
Trigger Innate Response: NK cells, Type IFNs, Neutrophils, Macrophages, Mast Cells, Complement, Cytokines
Trigger Adaptive Response: B cells, T cells, Ab's, Cytokines
resolution memory: apoptosis, memory cells