Dynamics Lecture 9 (Data normalisation: once you’ve run a
Dynamics Lecture 9
(Data normalisation: once you’ve run a
expression profiling experiment
, Temporal Clustering by Affinity Propagation (TCAP)
, Chromatin ImmunoPrecipitation (ChIP) can identify direct targets
- Which genes are differentially expressed/regulated?
, 1b) Do you think the data is 'sound'?
, 2) Which biological processes are regulated?
, 3) Which genes have similar responses?
), What do you get once you’ve run an expression profiling experiment?
, Correlation of gene expression
, Aim is not to just identify which genes are
regulated, but the mechanism of regulation
, Functional relationships represented by many types of edges connecting nodes in a qualitative ‘Multinetwork’