Please enable JavaScript.
Coggle requires JavaScript to display documents.
Cancer Treatment (Radiotherapy (Brachytherapy: Source in contact with…
Cancer Treatment
Radiotherapy
Advantages: Skin sparing, penetration, beam uniformity
Grey Unit: A unit of energy absorbed radiation equal to the does of 1 joule of energy/kg mass. /100 Rads
-
-
-
-
Chemotherapy
-
-
Adjuvant: Breast, lung, colorectal, pancreatic
Toxicity
Acute
Self limiting: Normal cells also affected, high growth (hair, skin, GI mucosa, bone marrow)
Long-term
-
-
Extravasation, vesicants (drugs causing tissue damage)
-
-
-
-
-
Curative: Acute leukemia, Hodgkin's
Drug resistance
-
Resistance to anthracyclines, alkyloids
-
Verapamil, quinidine, cyclosporine: Reverse MDR via competitive inhibiton
Radiotherapy Toxicity
Long-Term
Permanent, cells with high turnover
-
Necrosis of soft tissue: mucosal ulcers, vascular connective tissue
-
Xerostomia: Serous acinar cells, dental carries
-
-