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Alzheimer's Disease (Risk Factors (Age, Smoking, Alcohol, Familial…
Alzheimer's Disease
Pathophysiology
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Three forms: early-onset familial, early-onset and late-onset
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Abnormal extracellular accumulation of amyloid-β peptide (Aβ) in amyloid plaques and tau protein aggregation in intracellular neuro fibrillary tangles (NFTs) occurs
The loss of synapses, acetylcholine and other neurotransmitters contributes to the decline of memory, attention and other cognitive functions
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Diagnosis
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Clinical criteria such as history, memory test, labs and brain imaging
Treatment
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memory aids, maintaining or improve the hygiene, nutrition and health
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