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Infections

Systemic Infection- When an infection spreads to several sites and tissue fluids, usually in the bloodstream. Fungal: histoplasmosis, cryptococcosis

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Localized infection- Microbe enters the body and remains confined to a specific tissue

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• Viral: measles, rubella, chicken pox, AIDS
• Bacterial: brucellosis, anthrax, typhoid fever, syphilis
Fungal: histoplasmosis, cryptococcosis

Steps Involved When a Microbe Causes Disease in a Host

3.Survive immune response

4.Cause damage

2.Adhere

5.Exit

1.Entry

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• hooklets

• fimbrae

• slime layer

• capsule

• spikes

Four phases of infection & disease

Prodromal period-

Period of invasion-

Incubation period-

Convalescent stage-

• casule

• envelope(virus)

• Leukocidins