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Anaphylaxis and anaphylactic shock (Clinical presentation (Facial…

- - - - Adrenaline
        Indication: shock, airway swelling, resp difficulty
        E.g. 0.5mL of 1/1000 IM (adults) 0.15mL if <6y,
        0.3mL if 6-12y); IV if severe (specialist use)
        MOA: a1/2 and B1/2 agonist - vasoconstriction, bronchodilatation
        Route: IM via epipen if available; repeat 5m intervals
        NB. 50% dose for pts on TCAs, B-blockers or MAOIs
      - Antihistamines
        Indication: itch, prophylaxis
        E.g. 10mg chlorphenamine IV
        MOA: block H-R, preventing histamine release
        Route: IV initially
      - Nebulised B2 agonist
        Indication: bronchospasm
        E.g. salbutamol
        MOA: agonist B2, bronchodilation
      - Steroids
        Indication: ASAP all patients
        E.g. hydrocortisone 200mg IV