Please enable JavaScript.
Coggle requires JavaScript to display documents.
Neurocide (Healthy Ageing (frontal-striatal system affected: correspond to…
Neurocide
Healthy Ageing
-
-
-
-
-
-
-
-
alterations in white matter integrity in anterior regions: PFC, anterior corpus callosum
-
-
Alterations in neurotransmitter and neurotrophic factor signalling pathways (amplified in neurodegenerative disease): depletion of dopamine in substantia nigra neurons in normal ageing and PD, lower levels of brain-derived neurotrophic factor (BDNF) in ageing, AD and HD
ion dysregulation, energy depletion in synaptic terminals
-
-
-
-
-
-
-
-
-
-