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Ankylosing Spondylitis (Amyloidosis (Splenomegaly, Hepatomegaly, Carpal…
Ankylosing Spondylitis
A
rachnoiditis
A
ssociated conditions
Plantar fasciitis
Inflammatory bowel disease
Cauda equina syndrome
Ig
A
nephropathy
A
nterior uveitis
A
ortic Regurgitation or
A
ortitis
A
V nodal block
A
chilles tendonitis
A
tlantoaxial subluxation
A
pical pulmonary fibrosis
A
myloidosis
Splenomegaly
Hepatomegaly
Carpal tunnel syndrome
Renal amyloidosis
Radiological
Pelvic & Spine X-ray
Sacroilitis
Subchondral erosion
Subchondral sclerosis
Squaring of lumbar vertebra
Syndesmophytes
Bamboo spine (late)
Chest X-ray
Reticulonodular opacities over apical lung zones
Treatment
Non-pharmacological
Regular exercise eg swimming
Physiotherapy
Pharmacological
NSAIDS (1st line)
Sulphasalazine (only for peripheral joint disease)
Anti-TNF
Etanercept
Biologics
Adalimumab
Clinical
Examination
Reduced chest expansion
Reduced spine movment
Forward flexion
Lateral flexion
Positive Schober's test
History
Back pain & stiffness
Inflammatory pain
Worsened in the morning
Improves with exercise
Spirometry
Restrictive Lung
Persistent high disease activity despite conventional treatment
Clinical Features (10A's)