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SaraMatosImmune (INNATE DEFENSES (SKIN AND MUCOSAE: skin and mucus…
SaraMatosImmune
INNATE DEFENSES
SKIN AND MUCOSAE: skin and mucus membranes have a nearly impenetrable barrier, serves as a first line of defense against disease. Skin and mucosae also produce secretions that contain protective chemicals
CELLS AND CHEMICALS: the second line of defense. Contains nonspecific cellular and chemical devices that the body will use to identify and destroy any substances that could be possibly harmful
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All the innate defenses protect us from pathogens through variations of engulfing particles(phagocytes), watching out for infected/cancerous cells(NK cells), releasing chemicals for regulation(fever and inflammatory response), and production of proteins that enhance the innate defenses(antimicrobial proteins)
ANTIBODY ACTIONS
PRECIPITATION- soluble molecules becoming interconnected via antibodies, becoming too large to stay in their solution
ACTIVATION OF COMPLEMENT- lysis of the cell the antibody is bound to, chemicals released during this enhance the inflammatory response of the body
AGGLUTINATION- antibodies have 2 binding sites; each can attach to a different antigen. If the antigens are on different cells it causes them to clump together
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T LYMPHOCYTES
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HELPER T CELLS- direct the adaptive immune response by activating B cells, other T cells and macrophages
LYMPHOID ORGANS
PRIMARY LYMPHOID ORGANS:
Thymus and red bone marrow.
FUNCTION: Where B and T cells mature. Both B and T cells originate in the red bone marrow, B cells mature in the red bone marrow, T cells mature in the thymus.
SECONDARY LYMPHOID ORGANS:
Lymph nodes, tonsils, spleen, Peyer's patch, and appendix
FUNCTION: Where mature lymphocytes encounter their antigens and are activated, lymph nodes filter lymph.
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