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PENTAMIDINE (ADME (Metabolism: Pentamidine is primarily metabolized by …

- - - - A: 4mg/kg qOD (10 d)
        P: 4mg/kg qOD (7-10 doses)
    - - Visceral-
        A: 2-4 mg/kg (1-2 days) - 15-30 doses
        P: 3-4 mg/kg (on alternate day) - 10 inj
      - Cutaneous-
        A: 2mg/kg qOD (7 doses)
        P: 3-4 mg/kg (1 to 2 times weekly)
    - - A: 4mg/kg (2-3 w)
        P: 4mg/kg qOD (2 w)
  - - - A: HIV patient: 300mg once every 4 weeks
        (cannot tolerate - 350mg q2w)
        P: 300mg q4w @ 150mg q2w
    - - A: 600mg qOD (3 w)
        P: 600mg qOD (3w)