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10.AMINOGLYCOSIDES (indication/ clinical use (severe G-ve, complicated…

- - - - intracellular content leak
        
        enhance antibiotic uptake (needs energy) -anerobe x byk energy
- - - - shock: IM x (poor perfusion)
- - - - byk K+
      - tubular proteinuria (byk protein)
      - aminoaciduria (byk amino acid)
      - glycosuria (byk sugar)
    - - increase thirst
      - decrease urine output
      - increase creatinines
  - - - age
      - renal impairment
      - diuretic (subs buat diuresis-kencing byk)
  - - - muscle paralyse
      - resp. depression
    - - myasthenia gravis
      - parkinsons
      - severe hypocalcemia (sikit Calcium)
      - infant with botulism