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Sleep neurobiology (Flip flop switch (When awake hard to induce sleepiness…
Sleep neurobiology
Flip flop switch
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when homostatic S and C high, inhibit orexin, TMN and Raphe
When circadian alerting system up, Process C and S down, promote orexin, which inhibits VLPO
Control of REM sleep
GABAminergic neurons in sublateral dorsal (SLD) region of pons highly active during REM and inhibit REM-off
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