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ANTIEMETIC P1 (Antiemetics Classification (5-HT3 ANTAGONISTS (SEROTONIN…
ANTIEMETIC P1
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How drug act? (EMESIS)
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Absorb to systemic circulation & free to bind to any respiratory receptor causes transferring of information & start the impulsive the CTZ
Act on CTZ : APOMORPHINE
Stimulate POSTSYNAPTIC D2-TYPE receptors at caudate putamen in brain;
Act as dopamine agonist;
stimulate dopamine receptor in CTZ to send impulse to the vomit center
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