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Parvovirus (Characteristics (Icosahedral, non enveloped, Small (18 - 25…
Parvovirus
Characteristics
Icosahedral, non enveloped
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Pathogenesis
- Entry via oronasal exposure to faeces
- replication in pharyngeal lymphoid tissue
- Viraemia (1 - 5 days post infection)
- Subsequent localisation in particular organs
-> Dependent on age of the dog and area of dividing cells
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Neonate
- Cerebellum
- Lymphoid tissue
- Bone marrow
(panleukopenia)
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- Directly enters crypts of small intestines
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